Recent Publications

  1. Haller, S, Kapuria, S, Riley, RR, O'Leary, MN, Schreiber, KH, Andersen, JK et al.. mTORC1 Activation during Repeated Regeneration Impairs Somatic Stem Cell Maintenance. Cell Stem Cell. 2017;21 (6):806-818.e5. doi: 10.1016/j.stem.2017.11.008. PubMed PMID:29220665 PubMed Central PMC5823264.
  2. Rodgers, JT, Schroeder, MD, Ma, C, Rando, TA. HGFA Is an Injury-Regulated Systemic Factor that Induces the Transition of Stem Cells into GAlert. Cell Rep. 2017;19 (3):479-486. doi: 10.1016/j.celrep.2017.03.066. PubMed PMID:28423312 PubMed Central PMC5468096.
  3. Rodgers, JT. Deteriorating Infrastructure in the Aged Muscle Stem Cell Niche. Cell Stem Cell. 2016;19 (2):150-151. doi: 10.1016/j.stem.2016.07.008. PubMed PMID:27494671 .
  4. Rodgers, JT, King, KY, Brett, JO, Cromie, MJ, Charville, GW, Maguire, KK et al.. mTORC1 controls the adaptive transition of quiescent stem cells from G0 to G(Alert). Nature. 2014;510 (7505):393-6. doi: 10.1038/nature13255. PubMed PMID:24870234 PubMed Central PMC4065227.
  5. Kraus, D, Yang, Q, Kong, D, Banks, AS, Zhang, L, Rodgers, JT et al.. Nicotinamide N-methyltransferase knockdown protects against diet-induced obesity. Nature. 2014;508 (7495):258-62. doi: 10.1038/nature13198. PubMed PMID:24717514 PubMed Central PMC4107212.
  6. Hall, JA, Tabata, M, Rodgers, JT, Puigserver, P. USP7 attenuates hepatic gluconeogenesis through modulation of FoxO1 gene promoter occupancy. Mol. Endocrinol. 2014;28 (6):912-24. doi: 10.1210/me.2013-1420. PubMed PMID:24694308 PubMed Central PMC4042075.
  7. Tabata, M, Rodgers, JT, Hall, JA, Lee, Y, Jedrychowski, MP, Gygi, SP et al.. Cdc2-like kinase 2 suppresses hepatic fatty acid oxidation and ketogenesis through disruption of the PGC-1α and MED1 complex. Diabetes. 2014;63 (5):1519-32. doi: 10.2337/db13-1304. PubMed PMID:24458359 PubMed Central PMC3994960.
  8. Rodgers, JT, Rando, TA. Sprouting a new take on stem cell aging. EMBO J. 2012;31 (21):4103-5. doi: 10.1038/emboj.2012.281. PubMed PMID:23042560 PubMed Central PMC3492738.
  9. Rodgers, JT, Vogel, RO, Puigserver, P. Clk2 and B56β mediate insulin-regulated assembly of the PP2A phosphatase holoenzyme complex on Akt. Mol. Cell. 2011;41 (4):471-9. doi: 10.1016/j.molcel.2011.02.007. PubMed PMID:21329884 PubMed Central PMC3060660.
  10. Walker, AK, Yang, F, Jiang, K, Ji, JY, Watts, JL, Purushotham, A et al.. Conserved role of SIRT1 orthologs in fasting-dependent inhibition of the lipid/cholesterol regulator SREBP. Genes Dev. 2010;24 (13):1403-17. doi: 10.1101/gad.1901210. PubMed PMID:20595232 PubMed Central PMC2895199.